It is now firmly back, after ~6 months off the drug (due to cost) :/
I've managed to keep off the lost weight, through a lot of willpower, but winter will be a struggle I can tell.
[–] Sohcahtoa82 1 day ago
[–] _heimdall 21 hours ago
The looking down on people is the huge problem. It is at least in part a self control problem, and also who cares? Everyone has things they try to deal with, faults they don't even notice, etc.
In my opinion, saying it is often a self-control problem is calling a spade a spade. It isn't always that, there are other reasons people may struggle with obesity. But for those finding help in GLP-1 blockers it does seem to boil down to just eating less. And again, who cares? Demonizing and shaming people for lacking self-control in certain areas is just a pretty shitty way to treat people.
[–] Aerroon 22 hours ago
I've come to realize that some of this difference actually comes from low-effort activity like walking.
At 1796 kcal BMR your weight is 76 kg.
At 1896 kcal BMR your weight is 86 kg.
At 1996 kcal BMR your weight is 96 kg.
It is easier to just eat 100 kcal less, but it's also not unreasonable for people to walk more. 100 kcal gets burned in something like 30-60 minutes of walking.
And that 100 kcal is a 10 kg difference in weight in the long-term (22 lbs). The key is that people usually don't go for those walks to lose weight, they just happen naturally during their day due to other reasons.
[–] JKCalhoun 19 hours ago
Now, who knows, without the walking I might have been 10 pounds heavier, but it sure didn't bring my weight down.
The only thing that did (in my eight years of recording) was eating less.
I had to prepare for surgery some 7 or so years ago and started eating the smallest of meals out of fear that I might die before the operation could take place (I had a constriction in my intestinal tract that, if blocked, could cause my intestines to burst).
In that two months of fear and small portions I lost like 20 pounds.
In the 7 years since though, I have been unable to stay at the small portions. (Until Zepbound.)
[–] Viliam1234 12 hours ago
But then I took the pill (orforglipron) and the kilograms started disappearing.
[–] GeoAtreides 17 hours ago
You don't get the full calories from nuts because we're can not chew them so thoroughly that they're 100% bio-available. There were studies that confirmed it. Now, eating them as butter, that's another thing.
700+ calories of nuts is about 100g-150g?... it would be better if you ate them in one sitting, the satiety suppression would be stronger. And don't be afraid to eat them, as much as you want, as long as they're whole, with no coatings. Just don't washed them with Coke, juice, etc.
[–] gruturo 23 hours ago
Good news: they let the patent on Semaglutide lapse in Canada, and it’s already expired naturally in India and a bunch of South American countries. There are going to be accessible generics at some point.
[–] JKCalhoun 19 hours ago
[–] nujabe 1 day ago
If you ever tried water fasting first couple of days are gruelling but day 3 and 4 are significantly easier. Another natural hunger suppressant is cardio which reduces hunger.
[–] Sohcahtoa82 1 day ago
The hunger never went away.
[–] boringg 21 hours ago
[–] pedalpete 1 day ago
These include things like loading your body earlier in the day with heavy protein and fermented foods, eating proteins and vegetables before carbs (make less room for carbs), and of course there is still the lower stress, improve sleep and exercise.
I'm not suggesting these are replacements, but potentially like a micro-dose response.
[–] zemoerfi 1 day ago
These GLP 1 drugs are huge molecules with a GLP 1 shaped key on them. It's like a house key attached to a school bus. Once it's in your lock, that key is going to be a pain to remove.
Stimulating natural GLP 1 helps for a few minutes. Using these drugs can help for a week.
[–] Sohcahtoa82 1 day ago
I did try keto before. Heavy protein, low carbs. Everyone promised a high protein/fat/fiber diet with low starch/sugar was the secret to feeling full sooner and for longer.
Nope. Didn't change a damn thing. I was still hungry all the time.
My experience mirrors the GP. Ozempic really flipped the switch. See my other comment (https://news.ycombinator.com/item?id=50399564) for more.
[–] gib444 1 day ago
I don't really like fermented foods and I avoid dairy. Only have heavy carbs a few times a month. Mostly it's meat, vegetables, fruit. I've done various diets as a result of trying to fix other issues but none move the needle on the food noise
I've also had no stress for like, a year now due to my circumstances
[–] i2amsam 20 hours ago
On a glp I don’t need to carefully plan my diet because carb-heavy or greasy foods are unappealing to consider. It’s a very strange feeling for me to look at a big menu and realize I want to order the salad, not that I “should”, and my cholesterol levels fell by 66%
It wasn't until this week that I started feeling the effect, and so far, it's like...yeah. I don't feel this damn near constant urge to eat anymore.
It's so frustrating to deal with people who naturally eat sensibly and look down on overweight people and accuse them of not having self-control. They have a complete lack of empathy and assume that everyone else has the same properly-calibrated sense of hunger that they do. Guess what: not everyone does.
They have no idea what it's actually like. They'll eat a six-inch sub sandwich and feel full all the way to dinner. Maybe they'll eat a handful of nuts in the afternoon if they get snackish. Then they assume that's what life is like for me.
No. If I ate just the six-inch sandwich, my stomach wouldn't even tell me I'm satiated, let alone full. I'd have to eat the footlong. And I'd still be hungry two hours later. Yeah, I'd eat a handful of nuts. And then another. And another. Until eventually I've eaten 700+ calories from nuts and I'd still be fucking hungry.
And don't tell me "drink more water!". If anything, I was overhydrating. My urine was nearly clear and I'm pissing every hour.
Ozempic has flipped the switch, though admittedly I'm in a transition period for sure. I went out for dinner the other day, had a bowl of soup and only about 1/3rd of my main course. My stomach was feeling full, but something was still telling me to keep eating. Luckily the discomfort of fullness won out and I took the rest home. The next day, for lunch, I ate the leftovers, and I felt full afterwards, and didn't feel the urge to snack at all before dinner.
It's such a breath of fresh air. Is this what normal or "naturally thin" people experience? Hunger that reflects actual caloric needs, rather than some unnecessary urge to constantly keep adding things to the stomach?
EDIT: "It is now firmly back, after ~6 months off the drug (due to cost) :/"
That sucks. With my insurance, it's only $50 for a 4-week supply, but on the prescription form from Costco, it lists the "U/C" as $2,207, which my understanding means it would be $2,207 if I didn't have insurance.
The price of this drug is damn near criminal.